Inflexibility can be detrimental to a business for several reasons. Firstly, it hinders innovation as the company may resist adopting new technologies or practices. Secondly, it can lead to customer dissatisfaction since the business may fail to meet changing customer demands. Thirdly, inflexible businesses are often less resilient during economic downturns or market disruptions. Lastly, it can demotivate employees who may feel stifled by rigid policies and lack of growth opportunities.